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Symbol
Name
ID

Lhx3
LIM homeobox protein 3
MGI:102673

Phenotype annotations related to nervous system

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes	Decreased response to growth hormone stimulation test	Ectopic posterior pituitary	Anterior pituitary hypoplasia	Ectopic anterior pituitary gland	Hypopituitarism	Abnormal prolactin level	Pituitary hypothyroidism
Disease(s) Associated with LHX3
panhypopituitarism

Mouse Phenotypes

nervous system phenotype

abnormal pituitary gland morphology

abnormal Rathke's pouch apoptosis

abnormal Rathke's pouch development

abnormal corticotroph morphology

decreased gonadotroph cell number

decreased lactotroph cell number

absent lactotrophs

absent somatotrophs

absent thyrotrophs

absent adenohypophysis

adenohypophysis hypoplasia

abnormal pituitary gland development

absent pituitary intermediate lobe

small pituitary intermediate lobe

Availability

Mouse Genotype

Lhx3^tm1(cre)Slp/Lhx3^tm1(cre)Slp

Lhx3^tm1.1Sjr/Lhx3^tm1.1Sjr

Lhx3^tm1Lmgd/Lhx3^tm1Lmgd

*

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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